Richter Signs Term Sheet With Mithra for Sales of Donesta

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Hungarian pharmaceutical company Gedeon Richter on Tuesday said it signed a binding term sheet with Belgian peer Mithra Pharmaceuticals on the commercialization of Donesta, an estetrol-based product candidate for hormone replacement therapy in postmenopausal women, according to a report by state news wire MTI.

The parties intend to finalize their partnership, which extends to Europe, including Russia and the CIS, Latin America, Australia, and New Zealand, in Q1 2023.

Under the terms of the agreement, Mithra is eligible to receive upfront payments totaling EUR 55m as well as EUR 15m in additional milestone payments subject to regulatory achievements and "tiered low double-digit" royalties depending on net sales.

Mithra announced positive top-line results from Donesta phase 3 studies in menopausal women in January 2022.

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